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Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Colorectal cancer (CRC) is a complex heterogeneous disease characterized by multiple mutations affecting critical signaling pathways. Limitations in therapeutic treatments due to the development of resistance mechanisms, toxicity, and...
Epithelial tissues rely on the activity of stem cells to sustain their structure and proper functioning. These stem cells are responsible for generating various types of cells, that are essential for the tissue's normal homeostasis, ...
Investigating Biologic Repeatability at Different Biological Levels: The Genomic and Phenotypic Response to Parallel Phenotypic Artificial Selection in Drosophila Melanogaster and D. Simulans
Repeated evolution in biology is widespread among morphologic forms but also recognized at essentially all biological levels. Organisms achieving the same functional goal is reported at the level of simple biochemical pathways, complex...
Visual communication plays an important role in the evolution of organisms, as selection processes often rely on the organism's physical appearance. For example, mate choice—often by females selecting the most attractive males—can lead...
Hundreds of millions of liters of oil and natural gas are introduced to the ocean annually, yet the ecological consequences of hydrocarbon inputs into the marine environment are poorly understood. In particular, the role of microbes in...
A long-standing paradox in evolutionary biology is the maintenance of genetic variation in traits that are strongly tied to fitness. How is it that variation can be maintained in ecologically important traits when directional selection...
Understanding how a single genome can produce drastically different phenotypes is a central theme in evolutionary biology. It requires a keen understanding of the ecological, molecular, and genomic regulatory mechanisms driving...
Sexual Selection, Population Structure, and Gene Flow in the Trinidadian Guppy (Poecilia Reticulata): Insights for the Conservation of Genetic Variation
The diversity of life has fascinated evolutionary biologists since the conception of the field. Particularly captivating is the paradox of phenotypic variation found within a species: trait variation is required for adaptation, yet...
During S phase, chromosomes are replicated in a defined temporal order called the replication timing (RT) program. RT programs are evolutionarily conserved, cell-type specific, and particularly resistant to a wide-range of protein...
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.