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Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Zinc(II) ions and reactive oxygen species (ROS) have had broad implications on the health and wellness of living beings. This dissertation focuses on imaging techniques aimed at unraveling the function of these species in various...
Community of practice (CoP) of research data curators is a relationship group of data curators with shared values that comes together to network and share their knowledge and ideas. By joining the CoP of research data curators, members...
Reusability is part of the FAIR data principle, which aims to make data Findable, Accessible, Interoperable, and Reusable. One of the current efforts to increase the reusability of public genomics data has been to focus on the inclusion...
The mechanisms underlying the gestational and circadian timing of parturition in humans are not fully understood. Studies of the timing of initiation of spontaneous labor show a peak between 2400 and 0500. This peak in labor onset...
Between Proxy and Instrument: Reconstructing Past Weather Using Qualitative Human Observations in the Absence of Instrumental and Proxy Records: A Case Study from Shirley Plantation, Virginia USA
In this dissertation, I produce novel scientific knowledge about the weather of the past using subjective human observations in the absence of instrumental records in the United States. Using a handwritten plantation journal from Shirley...
The advent of high-throughput techniques has led to exponential increase in the size of biological data encoded in various formats and stored in different databases. This has posed challenges for biological scientists to retrieve, use, ...
The dissertation research is focused on improving performance on genome wide nucleosome positioning. Nucleosome is the basic structural unit of DNA in eukaryotic cells. As nucleosomes limit the accessibility of the wrapped DNA to...
The pancreas is an organ located in the abdomen. It is made up of exocrine cells and endocrine cells. In particular, the endocrine cells include hormone-producing cells that form clusters within the pancreas, called islets of Langerhans....
While the immune system is extraordinarily complex and powerful, and medical advancements are more spectacular than ever, in recent history we have seen the unfortunate failure of both processes (immune system and drugs) in the...
Circadian clocks are endogenous timekeepers, but they need to be synchronized, or entrained, with external cues such as solar time to stay in harmony with the external environment. The circadian clocks give selective advantages to humans...
Our DNA is under continuous stress by endogenous and exogenous attacks such as genotoxic chemicals, ionizing radiation, and metabolic products. DNA damage is extremely detrimental, even a single unrepaired damage is sufficient to kill a...
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
