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Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Prolactin is a protein hormone predominately synthesized in and secreted from cells in the anterior pituitary gland called lactotrophs. Although prolactin is elevated during other physiological states, mating induces a unique pattern of...
In this Dissertation, I detail how two vocal motor pathways (vocal motor pathway and anterior forebrain pathway) contribute to the vocal production in zebra finch adult song. I first describe a model of rapid dissolution and recovery...
As an RNA-guided RNA modification enzyme, the box H/ACA RNP recruits the guide RNA to recognize the substrate RNA, whereas the protein partners carry out the catalysis. Most intriguingly, box H/ACA RNPs share the same four conserved...
Of late, path-breaking advances are taking place and flourishing in the field of solid-state Nuclear Magnetic Resonance (ssNMR)spectroscopy. One of the major applications of ssNMR techniques is to high resolution three-dimensional...
Methods from shape analysis are used in morphometry, which is the quantitative analysis of macroscopic anatomical features. We assume that anatomy is flexible, and this brings us to the first problem of resolving how ``shape'' should be...
A central question of evolutionary biology concerns the study of evolvability. A growing body of theory implicates the pattern of genetic effect interactions underlying a trait, referred to as the genetic architecture of a trait, as an...
This dissertation presents and evaluates a theoretical method of eradication of invasive species through the use of Trojan Y chromosomes. The mathematical analysis of the Trojan Y chromosome eradication strategy is presented for the ODE...
The mechanism for cortical folding pattern formation is not fully understood. Current models represent scenarios that describe pattern formation through local interactions and one recent model is the intermediate progenitor model. The...
This dissertation is comprised of a variety of efforts towards the development of fast numerical methods and their applications, particularly in the context of simulating biological systems. Scientific computing of these problems...
In this dissertation, the neurobiological mechanisms that govern the effects of social buffering on stress were evaluated in female prairie voles (Microtus ochrogaster). As reviewed in Chapter 1, social living is beneficial for many...
The brain is one of nature's greatest mysteries. The mechanism by which the folds of the brain's cerebral cortex, called gyri (hills) and sulci (valleys), are formed remains unknown. Existing biological hypotheses that attempt to explain...
Signaling through the notch pathway originates upon interaction between the notch receptor and one of its two ligand proteins, delta or serrate. Extracellular binding of either ligand protein induces the release of the notch...
No-Reference Natural Image/Video Quality Assessment of Noisy, Blurry, or Compressed Images/Videos Based on Hybrid Curvelet, Wavelet and Cosine Transforms
In this thesis, we first propose a new Image Quality Assessment (IQA) method based on a hybrid of curvelet, wavelet, and cosine transforms, called the Hybrid No-reference (HNR) model. From the properties of natural scene statistics, the...
Anthracis Repressor (AntR) is a Mn(II) activated DNA binding protein that is involved in the regulation of Mn(II) homeostasis in Bacillus anthracis. AntR is a member of the Diphtheria Toxin Repressor (DtxR) family of proteins. These...
The classical Frenet frame is a moving frame on a smooth curve. Connecting a sequence of points in space by line segments makes a discrete curve. The reference frame consisting of tangent, normal and binormal vectors at each point is...
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