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Molecules containing the phosphate (O—PO32-) moiety are ubiquitous in biochemistry. Phosphoryl transfer reactions that break and form the O—P phosphoryl bond are central to biological processes as diverse as energy metabolism and signal...
Arginine kinase reversibly catalyzes phosphoryl transfer between ATP and arginine, thus providing a mechanism for buffering ATP levels in cells with high or variable energy requirements. X-ray crystal structures of a substrate-free and...
Despite the existence of structures of substrate-bound and substrate-free forms of two highly specific members of the family of phosphagen (guanidino) kinases, namely arginine and creatine kinase, the full determination of the structural...
Monoclonal antibody (mAb) A20 is the best characterized AAV2 neutralizing mAb [18, 116, 165]. Large quantities of the mAb A20 were obtained from hybridomas cell culture, and A20 Fab fragments were produced and purified by standard...
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