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Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Past research has shown that social rejection predicts a wide range of psychological problems, including the development of depression, anxiety, and aggressive behavior. In addition, rejection by others appears to maintain and exacerbate...
Pathological exercise (PE) is a common feature of individuals with eating disorders (ED) and represents a key maintaining factor of eating pathology. However, little is known about underlying mechanisms that maintain PE and whether these...
It is well established that estrogens suppress feeding primarily by reducing meal size, and that this is partly mediated by enhancement of the response to satiation signals. Glucagon-like peptide 1 (GLP-1) acts on receptor populations...
Menstrual status is known to influence thermoregulation, and fluid loss during exercise/heat stress may vary at different stages of the ovarian cycle in healthy women. It has been established that the steroid hormones, estrogen and...
OVX leads to hyperphagia and weight gain in female rats, which can be prevented by E2; however, the role of endogenous E2 on feeding and energy homeostasis in female mice has not been well characterized. The 2-part goal of this study was...
Recent research suggests that stress and reward insensitivity may interact to confer risk for Major Depressive Disorder (MDD). However, no study has yet examined stress and reward sensitivity, and their interaction, in the context of...
Increased stress and blunted reward processing are important risk factors and correlates of Major Depressive Disorder. The experience of acute stress has been shown to reduced fMRI correlates of reward processing; however, few studies...
What biological processes underlie self-control, such that this adaptive skill differs among people and appears to be functionally limited? The current research aims to answer this question by proposing that adenosine, an inhibitory...
Relationship conflict is a stressful experience for couples and stress can disrupt the balance within the immune system. In particular, stressful experiences tend to be linked with an upregulation of cytokines. In this study, I examined...
Background: The nutrient content and fluid retentive capacity of chocolate milk (CM) is beneficial for most athletes. However, nighttime consumption of CM has an unknown impact on next morning endurance performance and hydration status....
Assessing the Clinical Utility of Non-Invasive Brain Stimulation in the Treatment of Anxious Arousal and Sensory Hypersensitivity: A Targeted Transcranial Alternating Current Stimulation Study
The ability of transcranial alternating current stimulation (tACS) to augment underlying rhythmic fluctuations of neuronal activity provides meaningful implications in the treatment of neuropsychiatric disorders characterized by...
Eating disorders (EDs) are associated with increased risk for suicide. Recent research suggests that excessive exercise (EE), an ED compensatory behavior, may increase suicide risk via increasing one's capability for suicide which is...
Exercise motivated by unhealthy body image goals is a common feature of eating disorders. There is a lack of consensus about what constitutes unhealthy exercise, which has created difficulties for its assessment and likely contributed to...
Central glucagon-like peptide 1 receptor (GLP-1R) stimulation suppresses food intake, and hindbrain GLP-1 neurons project to numerous feeding-relevant brain regions. One such region is the nucleus accumbens (NAc), which plays a role in...
Evaluating Alpha Dysrhythmia across the Sensory Cortex and Default Mode Network as a Novel Neuropathophysiological Mechanism of and Therapeutic Target for Posttraumatic Stress Symptoms
Prevailing neurobiological models of posttraumatic stress disorder (PTSD) have focused on dysfunctions of a prefrontal-cortex-amygdala-hippocampal circuit in the top-down regulation of threat detection and emotion regulation....
The hypophagic effect of the ovarian hormone estradiol appears to be mediated by its ability to interact with multiple hormone, neuropeptide, and neurotransmitter systems implicated in the direct control of food intake. Nonetheless, the...
Accumulating evidence suggests that dysfunction in the neuroendocrine systems that influence feeding constitutes a key mechanism in the pathophysiology of disordered eating. The studies presented in this dissertation identify behavioral...
This study sought to replicate and extend previous research that used affective modulation of the eye-blink startle response (STR) to explore the emotional consequences of drinking. One of four levels of alcohol dose (including a no...
Bulimia nervosa (BN) is a serious eating disorder characterized by binge episodes and compensatory behaviors. It often persists for several years and is associated with increased medical complications and risk of death, underscoring the...
The goal of this study was to evaluate the effects of estrogen on cardiovascular regulation and fluid balance, while also controlling for body weight changes that occur as a consequence of ovariectomy and estrogen replacement. In terms...
Motivationally significant stimuli activate motivational systems to support perception and action. Rewards are naturally occurring motivationally salient stimuli that activate approach behaviors, for example, effort for a reward. Two...
Spatial learning is impaired in humans with preclinical Alzheimer's disease (AD), and we've previously reported similar impairments in a mouse model of AD. Spatial navigation impairments are one of the earliest symptoms to appear in this...
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
