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Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Changes in gene expression determine cellular differentiation and developmental programs as cells transform from a progenitor to a mature adult state. The difference in the organization of the nucleus between undifferentiated cells and...
Under normal physiological conditions, trypsin remains inactive as trypsinogen inside the pancreas. Upon entering the small intestine, trypsinogen is converted to active trypsin. Acute pancreatitis is caused by premature activation of...
In Escherichia coli, the argX gene is the first gene in a cluster with three other tRNA genes. The tRNA products of the three downstream genes, hisR, leuT and proM are abundant in E. coli, and all four of the tRNAs are processed from the...
Lipid oxidation pathways and nitric oxide signaling pathways are interrelating pathways with significance both separately and in conjunction (references 1-2). Lipid oxygenating pathways involve the formation of hydroperoxides, alkanes, ...
The hepatitis C virus (HCV) is a serious health threat globally. Current therapies are not tolerated well, have a low response rate, and there is no available vaccine. New viral targets for drugs are urgently needed. The aim of this...
Myocardial contractions are generated by the binding of myosin motor proteins to cardiac actin in the thin filament. This process is regulated by the binding of calcium ions to troponin C. When Ca2+ binds to site II of troponin C, the...
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
