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Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Self-sustaining oscillators regulate diverse aspects of physiology in mammals such as insulin secretion, cell cycle regulation, and circadian rhythmicity. The circadian clock is based upon several interacting feedback loops, which affect...
Circadian rhythms in mammals are generated by a negative transcriptional feedback loop in which PERIOD (PER) is rate-limiting for feedback inhibition. Casein kinases Iδ and Iε (CKIδ/ε) can regulate temporal abundance/activity of PER by...
Circadian clocks are endogenous timekeepers, but they need to be synchronized, or entrained, with external cues such as solar time to stay in harmony with the external environment. The circadian clocks give selective advantages to humans...
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.