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Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
The photophysical characteristics of 5-arylvinyl-5Oe-methyl-2, 2Oe-bipyridyls (AVMB) and their zinc complexes were investigated in order to recognize the factors that influence the emission band shift and fluorescence quantum yield change...
Polyelectrolytes can be used in a variety of forms from Layer-by-Layer assembled thin films to spun polyelectrolyte complex as free-standing membranes. The Layer-by-Layer methodology is used to adsorb oppositely charged polyelectrolytes...
The central focus of this thesis is a study of materials with competing magnetic interactions and understanding how these interactions affect the overall magnetic behavior of solids. Understanding the fundamental factors that can be used...
Oxide ceramics are materials with a wide range of properties. Insulators are most common, however semiconductors, strongly correlated electron materials, and even superconductors are all relevant oxide materials. Here we seek to...
This dissertation presents the first single crystal 55Mn NMR characterization of three compounds related to Mn12-acetate [Mn12O12(O2CCH3)16(H2O)4]× 2CH3COOH-4H2O (henceforth Mn12-Ac) that have come to be known as Single-Molecule Magnets ...
Many industrially important heterogeneous catalytic reactions are not well understood. This lack is mainly due to the high reactivity and transient nature of the reactive sites and chemical intermediates involved. Monolithic, sol-gel...
Transparent hybrid polymers created through thiol-ene click chemistry were obtained. Methacrylate and acrylate capped zirconium oxo-clusters (ZOCs) were incorporated into two thiol-ene polymer networks. The vinyl capping groups...
This dissertation presents studies by magnetization, dc magnetic susceptibility and EPR spectroscopy on several new spin-frustrated polyoxometalate (POM) lattices of increasing spin sizes and complexities. Measurements have been made...
The hydraulic analogy for electrical circuits is a well-known, if limited, model for understanding potential and current. The work described in this thesis extends this analogy to chemical reactions by constructing apparatuses that model...
This dissertation has focused on studying the electron spin dynamics in the quantum and classical limit and, most importantly, at the quantum-classical boundary. We have successfully used high frequency electron paramagnetic resonance ...
Nanotechnology is a new frontier for the advancement of science and technology. Nanomaterials are playing a crucial role and that they will continue to do so is beyond doubt. They are being used in electronic, magnetic, optical and...
The actinide elements are playing larger roles in modern life, finding uses in nuclear energy, remote power sources, medical uses as radiotherapy isotopes, as well as in geological applications in nuclear tools. However, due to their...
Solid films of C60 and C70 fullerenes are evaluated in propylene carbonate/lithium perchlorate, an electrolyte commonly used in lithium batteries. Cyclic voltammetry, chronopotentiometry, and an effusion test, show that reduced C60 and...
Solid-state carbon-13 nuclear magnetic resonance (NMR) spectroscopy has come to be considered the pre-eminent analytical technique for the study of soil organic matter in its entirety. Despite its widespread use, carbon-13 CP-MAS NMR of...
Block copolymer ionomers are a class of polymers that contain a hydrophobic block and a block containing charged repeat units. In the first set of experiments, micelles were created from such a polymer. A set of fluorescence probe...
Box C/D snoRNPs catylze the specific 2'O-methylation of rRNA in important regions the ribosome, although the role of the modifications is unclear. Eukaryotic box C/D snoRNPs consists of a box C/D RNA and four proteins, Fibrillarin, Nop56...
Microwaves have been for their ability to heat water and food rapidly. And thanks to scientific technology and global marketing, the microwave oven was invented and got widely used in 1970's and 1980's. . Microwave radiation has specific...
Nanoparticles have been extensively studied in the past few decades due to the possibilities they offer in applications ranging from medicine to energy generation. A new class of ultra-small noble metal nanoparticles consisting of tens...
This work describes the activation profiles and regulatory cascades of the human kallikrein-related peptidases. The human kallikrein (KLK)-related peptidases are the largest family of serine peptidases, comprising 15 members (KLK1–15)...
The stationary phase used in a chromatography column and the way it is packed inside the column greatly influences the separation in a chromatographic system. In capillary electrochromatography, the column plays an even more vital role...
Electron transfer dynamics at the nanocrystalline semiconducting metal oxide interface plays a pivotal role in diverse applications such as dye-sensitized solar cells (DSSCs), dye-sensitized photoelectric solar cells (DSPECs), sensors...
Damage continues to plague the structural integrity of polymer composites. Continued stress leads to cracking and weakening of a composite system. Engineering polymer composites with carbon nanotube reinforcements and self-healing...
Spin-crossover (SCO) is one of the most recognized spin-state switching phenomena as an example of molecular bistability. The ability to convert between high spin and low spin electronic configurations in a transition metal center under...
Solution-Phase Hydrogen/Deuterium Exchnage Monitored by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry: Technique Development and Application to Muscle Biochemistry
Proteins are vital macromolecules of every living cell. They undertake a variety of tasks that are essential for life. Most proteins function in assemblies rather than individually. Protein function is strongly correlated to structure...
Small nucleolar RNAs (snoRNAs) are localized in the nucleolus as small ribonucleoprotein particle (snoRNP) that are RNA-protein complexes and catalyze site specific modifications on the ribosomal RNA. When compared to many protein...
This dissertation studies the size- and site-dependent optical and magnetic properties of II-VI quantum dots (QDs). The first chapter provides a theoretical background used to analyze the data and the properties expected for diluted...
Extended Metal Atom Chains (EMACs) are compounds that consist of three or more metal atoms that are directly bonded with the support of equatorial organic ligands. This dissertation is focused on the high frequency electron magnetic...
Petroleum, one of the most complex mixtures on Earth, has been extensively studied for decades. Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) and the ultrahigh resolution it provides, however, has dramatically...
CRISPR-cas systems have been found to confer RNA guided immunity in prokaryotes comparable to the eukaryotic RNA interference. These Clustered Regularly Interspaced Short Palindromic Repeats, as their name entails, are repeated sequences...
One of the mechanisms of cardiac arrhythmias is the self-organization of electrical waves in the heart. These waves can anchor to scar tissue, collagen fibers, and coronary vessels. The anchoring generates stationary electrical signals...
All functional RNAs contain post-transcriptionally modified nucleotides. 2'-O-ribose methylation and pseudouridylation are the two major types of modifications, which occur by box C/D and box H/ACA ribonucleoprotein (RNP) complexes, ...
Human glucokinase is a 52 kDa single polypeptide chain containing 465 amino acids and a single binding site. It catalyzes the ATP dependent phosphorylation of glucose in the beta pancreatic cells, which ultimately serves as the glucose...
Our lab was faced with a synthetic challenge during studies towards the total synthesis of the anti-malaria drug, artemisinin. Known methods such as the Aldol condensation, the Horner-Wadsworth-Emmons and the Wittig reactions were...
Materials synthesis far from thermodynamic equilibrium can yield hierarchical order that spans from molecular to macroscopic length scales. Here we study the formation of microscopic and macroscopic inorganic tubes during spatially...
Two-dimensional gel electrophoresis (2-DE) is used to compare the protein profiles of different crude biological samples. Narrow pH range Immobilized pH Gradient (IPG) strips were designed to increase the resolution of these separations....
Controlling particularly reactive substances to achieve desired outcomes is a constant challenge in materials chemistry. Reactants and products consisting of main group and transition metal elements often exhibit extreme sensitivity to...
This dissertation describes experimental methodologies and their application for the study of chemical self-organization in micropatterned reaction systems. The general approach is based on office-printer-assisted soft lithography and...
Breast cancer is the second leading death-causing cancer in women, after lung cancer. Breast cells are normally responsive to the estrogen hormone as they have the receptor for it. Breast cancer types that express the estrogen receptor...
Reproduced with permission from Journal of the American Chemical Society, submitted for publication. Unpublished work copyright 2008 American Chemical Society. The development of ternary nanoscale materials with controlled cross...
This dissertation is organized in two parts. The first part summarizes work in a newly developed synthetic route to perovskite-like MOFs, offering control over particle size and morphology. The second part of the dissertation cover...
Orientational restraints resulting from a wide range of anisotropic nuclear spin interactions such as chemical shifts, heteronuclear dipolar interactions, and quadrupolar interactions, have been widely used for determining the structures...
Spin crossover (SCO) is a phenomenon of magnetic switching in transition metal complexes that can exist in two different electronic configurations, depending on the splitting of d-orbitals by the surrounding ligand field. About 90% of...
Exploration of High Temperature Ethanol/Water Mobile Phases as a Green Alternative to Traditional Reversed Phase High Performance Liquid Chromatography
Reversed phase liquid chromatography is a common analytical technique employed in a variety of fields as a core component in many developmental and validation methods. Traditionally, this technique uses acetonitrile/water or methanol...
Gold-catalyzed organic transformations have been a hot topic of research in synthetic organic community over the last few years. Amazingly, most of the reactions can be performed under mild conditions using a catalytic amount of gold...
The focus of this dissertation is to study the magnetic properties of several novel transition metal complexes, with particular emphasis on using SQUID magnetometry alongside electron paramagnetic resonance (EPR) and spectral simulations...
IdeR is an iron-dependent repressor protein, one of the essential proteins found in Mycobacterium tuberculosis. IdeR is a homologue of the diphtheria toxin repressor (DtxR). IdeR controls iron acquisition and storage, moreover it binds...
Box H/ACA ribonucleoprotein particle (RNP), an RNA-guided RNA modification enzyme, is comprised of four conserved proteins (Cbf5, Nop10, Gar1 and L7Ae) and one guide RNA. This complex recognizes the substrates by the guide RNA and...
Crystalline intermetallic phases grown by metal flux synthesis are discussed in terms of structure-property relationships. Flux growth is employed as the primary synthesis methods across different systems from single element fluxes like...
Metal flux synthesis is a useful technique for the discovery of novel intermetallic phases. The molten state enhances diffusion rates which improves rates of reaction. Reactions can proceed at lower temperatures, allowing for the...
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