Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
In this paper I analyze and critique Gert's views on death, tracing the evolution of his ideas throughout his career. I argue that the definitions-criteria-tests framework that he and his colleagues introduced, along with their approach...
OBJECTIVE: To examine the association between personality traits and longevity. METHODS: Using the Guilford-Zimmerman Temperament Survey, personality traits were assessed in 2359 participants (38% women; age = 17 to 98 years, mean = 50...
Heparin does not appear to improve overall outcomes when used for ischemic stroke or within the first 2 weeks of a cardioembolic stroke. (SOR B, extrapolated from meta-analyses of multiple heparinoids.)
INTRODUCTION: Cardiovascular disease (CVD) remains the leading cause of mortality in United States (US) [1], and the inevitable process of aging, or one's age, remains the primary unmodifiable risk factor and independent predictor of CVD...
There is a well-established relationship between the olfactory and the endocrine systems. At the center of this relationship sits the olfactory bulb, which acts as a relay station for the sense of smell. In fact, neurons in the olfactory...
Although cognition declines with age, cancer may increase that decline, either through cancer treatment or decreased quality of life (QOL) accompanied with increased anxiety and depression. Cross-sectional research shows that more active...
Introduction: The popularity of endurance events has grown recently with an increased number of participants who have an elevated body fat percentage. The influence of chronic endurance training on adipose tissue physiology in these...
Older adults are vulnerable to glucocorticoid-induced muscle atrophy and weakness, with sex potentially influencing susceptibility to those effects. Aerobic exercise can reduce glucocorticoid-induced muscle atrophy in young rodents....
The present research addressed fundamental questions about the visual perspective of autobiographical memories: Are stable personality characteristics associated with visual perspective? Does visual perspective influence the memory's...
Cefotaxime, ceftriaxone, and respiratory fluoroquinolones are recommended for influenza-associated pneumonia. Oseltamivir and zanamivir can be used to reduce viral shedding in hospitalized patients with influenza, with or without...
Breast cancer survivors (BCS) encounter side effects from cancer treatments that negatively affect muscular strength and body composition, particularly the loss of lean mass. Studies have shown that resistance training (RT) can maintain...
The human cardiac troponin I (hcTnI) mutation R145W has been associated with restrictive cardiomyopathy. In this study, simultaneous measurements of ATPase activity and force in skinned papillary fibers from hcTnI R145W transgenic mice ...
The controversy surrounding the dead donor rule and the adequacy of neurological criteria for death continues unabated. However, despite disagreement on fundamental theoretical questions, I argue that there is significant (but not...
Purpose. The primary purpose was to determine the effect of sleep time on performance during a 3-day multistage ultra-endurance triathlon (stage 1: 10km swim, 144.8km bike; stage 2: 275.8km bike; stage 3: 84.4km run). Methods. Eighteen...
PURPOSE: Diving operations may require personnel to be immersed for extended periods while breathing compressed air or 100% O2. The main objective of this study was to investigate the physiological effects of single and repetitive diving...
Peripheral Artery Disease (PAD) is a vascular disease that affects over 8 million Americans. PAD patients commonly have vascular dysfunction and difficulty walking due to pain in the legs during physical exertion. Walking therapy has...
Calcitonin has been shown to improve acute pain at rest in patients with osteoporotic vertebral fractures, when compared with placebo, and reduce the use of other analgesic medications (SOR A, based on a meta-analysis of randomized...
Coenzyme Q10 (CoQ10) may lower systolic and diastolic blood pressures in patients with primary hypertension, but is not recommended as an antihypertensive treatment (SOR: C, systematic review of low-quality RCTs using disease-oriented...
Introduction: Due to the high metabolic demand of sport, it is essential that athletes meet their caloric need to support training, recovery, and muscle growth. Consuming protein before sleep may have positive effects on sleep, overnight...
Previous studies investigating the effects of high altitude (1500 – 3500 m) exposure on energy balance demonstrate various physiological adaptations that support negative energy balance, such as increases in resting metabolic rate and...
BACKGROUND: Frailty syndrome is a geriatric medical condition characterized by diminished muscular strength and endurance, weight loss, and weakened physiologic function. Frailty syndrome tends to manifest itself amongst morbidities and, ...
Muscle atrophy decreases physical function and overall health. Increased glucocorticoid production and/or use of prescription glucocorticoids can result in a myopathy that presents with significant muscle atrophy and weakness....
Background: Female aesthetic athletes strive to attain an ideal body image for their sports. Dancers in particular pose an addition issue in that they are performing artists and are often not considered athletes. The physical demands...
Background: Skeletal muscle is highly responsive to exercise training stresses, resulting in specific performance improvements based on the type of training undertaken (66, 119). Among all the variations of exercise training there are...
Traumatic brain injury (TBI) induces acute alterations in cerebral blood flow (CBF) autoregulation and cerebral artery contractility, which increases the risk of developing neurodegenerative diseases, as well as ischemic and hemorrhagic...
BACKGROUND: The growth in popularity of women's soccer has led to an increased interest in the physical, physiological, and technical demands for these athletes. To meet these demands, optimal preparation and recovery are necessary. One...
Ecophysiology of Ectothermic Ecosystem Engineers: Bioenergetic Effects of Climate and Food on Dominant Consumers and Their Consequences for Coastal Ecosystems
This body of work explores dynamics of temperate marine grazers that are sensitive to food availability and inhabit regions with dramatic contemporary variation in abiotic conditions due to nearshore upwelling. Climate change projections...
The Uniform Determination of Death Act (UDDA) states that an individual is dead when "all functions of the entire brain" have ceased irreversibly. However, it has been questioned whether some functions of the hypothalamus, particularly...
The number of women participating in resistance training has increased from 14.4% in 1994 to 21.0% in 2010 (418). Resistance training is known to enhance body composition (20); however, the effects of an acute bout of resistance exercise...
The skeletal muscle clock contributes to the regulation of skeletal muscle health and function. Mutations to the muscle clock result in decreased muscle mass and strength, diminished mitochondrial health, and altered substrate metabolism...
Due to the constant mental, physical, and thermal stress of firefighting, it is imperative to explore interventions that may mitigate any negative health effects the occupation brings to firefighters. One of those risks is heat related...
A large body of evidence links antagonism-related traits with cardiovascular outcomes, but less is known about how psychological traits are associated with intermediate markers of cardiovascular disease. Using a large, community-based...
College students (N=3, 435) in 26 cultures reported their perceptions of age-related changes in physical, cognitive, and socioemotional areas of functioning and rated societal views of aging within their culture. There was widespread...
Temporal Lobe Epilepsy (TLE) is the most common form of epilepsy in adults, and patients with TLE often suffer from seizures refractory to antiepileptic drugs. A deeper understanding of the pathophysiology of TLE is critical for...
INTRODUCTION: Obesity is associated with increased cardiometabolic disease risk, although the vascular and metabolic features of obesity are often studied independently. Resistance to both insulin-mediated suppression of lipolysis and...
While the overall survival rate for breast cancer has improved, breast cancer survivors (BCS) are still left with the negative side effects from cancer treatments that affect body composition. Cancer treatment side effects can cause a...
Hypogonadism contributes to limb skeletal muscle atrophy by increasing rates of muscle protein breakdown. Androgen depletion increases markers of the autophagy-mediated protein breakdown pathway that persist throughout the diurnal cycle....
BACKGROUND: It is well-documented that ingesting carbohydrate prior to exercise attenuates fat oxidation. However, it is yet to be established whether this effect is primarily the result of alterations in the mobilization of free fatty...
Cardiovascular disease (CVD) is the leading cause of death, with age being the strongest predictor of cardiovascular health. Age-related changes to the vasculature such as endothelial dysfunction and arterial stiffening are believed to...
Robotic assistive devices hold enormous promise for augmenting and rehabilitating human locomotion (e.g. exoskeletons). Existing control techniques for lower-body exoskeletons, however, take significant time to design and tune because...
BACKGROUND: Nutrient timing is an effective means of augmenting endurance exercise training and performance. Previous studies report that pre-exercise feeding can influence exercise metabolism up to 4 hours post-prandial. However, this...
Background: The nutrient content and fluid retentive capacity of chocolate milk (CM) is beneficial for most athletes. However, nighttime consumption of CM has an unknown impact on next morning endurance performance and hydration status....
Associations among personality as measured by the Five Factor Model, physical activity, and muscle strength were assessed using data from the Baltimore Longitudinal Study of Aging (N = 1220, age: mean = 58, SD = 16). General linear...
The Effects of Resistance Training and Protein Supplementation on Body Composition, Muscular Strength, and Physical Function in Transcatheter Aortic Valve Replacement Patients
BACKGROUND: Approximately 5-6% of older individuals ≥75 years of age will develop aortic stenosis and require aortic valve replacement via transcatheter aortic valve replacement (TAVR). Due to most patients not surviving ≥5 years post...
Pre-sleep protein has been shown to improve overnight muscle protein synthesis, muscle size and strength, and muscle recovery. However, all pre-sleep protein studies to date have utilized dairy-based protein sources. There is currently a...
Recommended first-line antibiotic therapy for community-acquired (CA) pneumonia is 5 days of a macrolide in adults and 3 to 5 days of amoxicillin in children. (SOR: C, based on consensus guidelines.) In otherwise healthy adults, there is...
Alcoholic myopathy is a wasting condition that effects skeletal muscle mass. One factor that may contribute to alcoholic myopathy is anabolic resistance which is induced by alcohol intake and leads to a suppression of protein synthesis...
Personality traits and cardiorespiratory fitness in older adults are reliable predictors of health and longevity. We examined the association between personality traits and energy expenditure at rest (basal metabolic rate) and during...
Adiponectin is a protein hormone most commonly produced by adipose tissue that has been found to play an important role in regulating vascular smooth muscle cell (VSMC) phenotype. In this dissertation we hypothesize that adiponectin...
Introduction: Heat stress is responsible for increases in all-cause mortality and results in thousands of deaths globally each year. These deaths occur both through active means (e.g. exertional heat stroke) and passive means (e.g. heat...
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
