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Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
The tendency to seek stimulating activities and intense sensations define excitement-seeking, a personality trait akin to some aspects of sensation-seeking. This trait is a central feature of extraversion and is a component of the...
CONTEXT: Recent studies have shown an association between cigarettes per day (CPD) and a nonsynonymous single-nucleotide polymorphism in CHRNA5, rs16969968. OBJECTIVE: To determine whether the association between rs16969968 and smoking...
BACKGROUND: Personality traits are considered risk factors for drug use, and, in turn, the psychoactive substances impact individuals' traits. Furthermore, there is increasing interest in developing treatment approaches that match an...
Nicotine use during adolescence is associated with the development of many debilitating pathologies in adulthood such as anxiety and depression. Adolescence is a time of many social pressures and biological changes occurring within the...
The world of primary care can be complex and challenging. With an ever increasing body of medical knowledge, primary care physicians must make it a priority to think outside the box when diagnosing patients. This is especially true when...
This experiment was designed to examine the impact of chronic stress exposure on nicotine consumption. Adolescent (postnatal days, PD 38-75) male mice underwent 10 days of social defeat, were treated with one month (long-term) of forced...
The Screener and Opioid Assessment Measure for Patients with Chronic Pain (SOAAP) and the Opioid Risk Tool (ORT) are both validated tools that screen for future problems with prescription opioids. The ORT has been more rigorously studied...
AIMS: Investigating the association between personality traits and smoking status using a comprehensive model of personality, the Five-Factor Model (FFM). DESIGN: Cross-sectional survey. Setting Baltimore, MD, USA. Participants Adult...
Smoking is a leading global cause of disease and mortality. We established the Oxford-GlaxoSmithKline study (Ox-GSK) to perform a genome-wide meta-analysis of SNP association with smoking-related behavioral traits. Our final data set...
Major depressive disorder is a serious public mental health concern with prevalent sex differences, affecting twice as many women as men. The non-competitive NMDA receptor antagonist ketamine is being used clinically at low doses as an...
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
