Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Naples, A., Katz, L., & Grigorenko, E. L. (2012). Lexical decision as an endophenotype for reading comprehension: an exploration of an association. Development And Psychopathology. Retrieved from http://purl.flvc.org/fsu/fd/FSU_pmch_23062302
Based on numerous suggestions in the literature, we evaluated lexical decision (LD) as a putative endophenotype for reading comprehension by investigating heritability estimates and segregation analyses parameter estimates for both of these phenotypes. Specifically, in a segregation analysis of a large sample of families, we established that there is little to no overlap between genes contributing to LD and reading comprehension and that the genetic mechanism behind LD derived from this analysis appears to be more complex than that for reading comprehension. We conclude that in our sample, LD is not a good candidate as an endophenotype for reading comprehension, despite previous suggestions from the literature. Based on this conclusion, we discuss the role and benefit of the endophenotype approach in studies of complex human cognitive functions.
Naples, A., Katz, L., & Grigorenko, E. L. (2012). Lexical decision as an endophenotype for reading comprehension: an exploration of an association. Development And Psychopathology. Retrieved from http://purl.flvc.org/fsu/fd/FSU_pmch_23062302
