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Certain alkoxy substituted taxanes and pharmaceutical compositions containing them. (1993). Certain alkoxy substituted taxanes and pharmaceutical compositions containing them. Retrieved from http://purl.flvc.org/fsu/fd/FSU_uspto_5243045
A taxane derivative of the formula ##STR1## wherein R.sub.1 is phenyl or substituted phenyl, PA0 R.sub.3 is CH.sub.3 O--, or CH.sub.3 CH.sub.2 O--, PA0 Z is --OT.sub.1, PA0 T.sub.1 is hydrogen, hydroxyl protecting group, or --COT.sub.2. PA0 T.sub.2 is H, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkenyl, C.sub.1 -C.sub.6 alkynyl or monocylic aryl, PA0 Ac is acetyl, and PA0 E.sub.1 and E.sub.2 are independently selected from hydrogen and functional groups which increase the water solubility of the taxane derivative are useful as antitumor agents.
Certain alkoxy substituted taxanes and pharmaceutical compositions containing them. (1993). Certain alkoxy substituted taxanes and pharmaceutical compositions containing them. Retrieved from http://purl.flvc.org/fsu/fd/FSU_uspto_5243045
