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Processes for the preparation of docetaxel. (2009). Processes for the preparation of docetaxel. Retrieved from http://purl.flvc.org/fsu/fd/FSU_uspto_7550608
The present invention provides processes for the production of docetaxel. Docetaxel is produced by protecting the C(7) and the C(10) hydroxy groups of 10-DAB with a bridging silicon-based protecting group. The resulting 7,10-protected 10-DAB derivative is then derivatized and deprotected to form docetaxel.
Processes for the preparation of docetaxel. (2009). Processes for the preparation of docetaxel. Retrieved from http://purl.flvc.org/fsu/fd/FSU_uspto_7550608
