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Method for preparation of taxol using an oxazinone. (1992). Method for preparation of taxol using an oxazinone. Retrieved from http://purl.flvc.org/fsu/fd/FSU_uspto_5136060
Process for the preparation of a taxol intermediate comprising contacting an alcohol with an oxazinone having the formula: ##STR1## wherein R.sub.1 is aryl, heteroaryl, alkyl, alkenyl, alkynyl or OR.sub.7 wherein R.sub.7 is alkyl, alkenyl, alkynyl, aryl or heteroaryl; R.sub.2 and R.sub.5 are independently selected from hydrogen, alkyl alkenyl, alkynyl, aryl, heteroaryl, and OR.sub.8 wherein R.sub.8 is alkyl, alkenyl, alkynyl, aryl, heteroaryl, or hydroxyl protecting group; and R.sub.3 and R.sub.6 are independently selected from hydrogen, alkyl, alkenyl, alkynyl, aryl and heteroaryl.
Method for preparation of taxol using an oxazinone. (1992). Method for preparation of taxol using an oxazinone. Retrieved from http://purl.flvc.org/fsu/fd/FSU_uspto_5136060
