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Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Stroke is a leading causing of death and disability world-wide, and yet, few options for therapeutic treatment exist. Cell therapies, particularly human bone-marrow derived mesenchymal stem cells (hMSC), have elicited particular interest...
Nanoparticle based cellular therapies hold great promise for clinical applications and medicinal use in human patients by allowing for targeted delivery of a personalized medicine payload to specific cells and tissues in a variety of...
Plant cytogenetics has continued to flourish and make essential contributions to genomics projects by delineating marker order, defining contig gaps, and revealing genome rearrangements. Here we review the field of plant cytogenetics...
Determining the equivalence or non-inferiority of a new drug (test drug) with a existing treatment (reference drug) is an important topic of statistical interest. Wellek (1993) pioneered the way for log-rank based equivalence and non...
Hop (Humulus lupulus L.) is an important crop worldwide, known as the main flavoring ingredient in beer. The diversifying brewing industry demands variation in flavors, superior process properties, and sustainable agronomics, which are...
Plants regulate gene expression at the transcriptional and post-transcriptional levels to produce a variety of functionally diverse cells and tissues that ensure normal growth, development, and environmental response. Although distinct...
The Relationship between Protein Intake on Factors Associated with Glycemic Control and Cardiovascular Health in Individuals with Pre-and Type 2-Diabetes
Background and Significance: The incidence of type 2 diabetes mellitus (T2DM) and pre-diabetes continues to increase. Many individuals are not aware of having the disease or early stages of the disease, pre-diabetes, until symptoms...
Migraine is a disabling, multifactorial recurrent neurological disorder. Affecting approximately 38 million people in the United States alone, migraine is recognized by the World Health Organization as the 7th most disabling condition, ...
Atherosclerosis is the leading cause of death among all age-related diseases. One potential way to attenuate aging is to reduce the accumulation of aging cells, also called senescent cells. Our lab previously reported that zinc overload...
Traumatic brain injury (TBI) induces acute alterations in cerebral blood flow (CBF) autoregulation and cerebral artery contractility, which increases the risk of developing neurodegenerative diseases, as well as ischemic and hemorrhagic...
Purpose: Adequate skeletal perfusion is necessary to maintain bone remodeling processes and bone health. Natural aging leads to progressive bone loss, which may be associated with impaired bone vasomotor function and impaired perfusion....
Ego depletion was initially understood as the exhaustion of an energy resource, possibly blood glucose. Recent work has favored a model based on allocation of energy in which motivation and beliefs change patterns of allocating energy...
The Clinical Application of Periodized Resistance Training during a 12-Week Hypocaloric Treatment for Obesity: A Joint Retrospective and Prospective Single-Center Study
Introduction. Medically prescribed very-low calorie diet (VLCD) systems have shown efficacy in producing clinically significant weight-loss in obese patients. This loss in bodyweight (BW), however, cannot be solely accounted for by...
Background and Significance: MetS encompasses a cluster of cardiometabolic abnormalities that increase the risk for developing chronic diseases including cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). Its prevalence...
Electrical properties (EP), namely conductivity and permittivity, can provide endogenous (having an internal origin) contrast for tissue characterization. EP of the biological tissue are strongly related to essential determinants of the...
In this essay we present analysis examining the basic dietary structure and its relationship to mortality in the first National Health and Nutrition Examination Survey (NHANES I) conducted between 1971 and 1975. We used results from 24...
Nutritional Status and the Relationship of Dietary and Serum Advanced Glycation End-Products with Inflammation, Oxidative Stress and Healing of Diabetic Foot Ulcers
Purpose: This study examined dietary and anthropometric components of diabetic patients with or without diabetic foot ulcers (DFU) and the association between advanced glycation end-products (AGE) and serum markers of oxidative stress...
Background and Significance: Diabetic foot ulcer (DFU) is one of the most devastating side effects of diabetes. It occurs in a diabetic patient as a result of neuropathy and or peripheral arterial disease of the lower limb. DFU has been...
Menopause leads to an increased risk for osteoporosis in women. Although drug therapies exist, increasing numbers of people prefer alternative therapies such as dietary supplements, e.g. calcium, vitamin D, and collagen hydrolysates for...
Osteoporosis has significant public health importance for both women and men, where 54% of the U.S. population age 50 and older have low bone mineral density (BMD). Chronic inflammation alters bone remodeling, which is one contributor to...
Since antiquity, alkaloid natural products have served as medicinal ingredients that still contribute as an inspiration for the development of novel therapeutics. For the synthetic chemist, much of the importance of natural products lies...
Bulimia nervosa (BN) is a serious eating disorder characterized by binge episodes and compensatory behaviors. It often persists for several years and is associated with increased medical complications and risk of death, underscoring the...
Introduction: Inflammation has been shown to play a role in a variety of disease states including osteoporosis and cardiovascular disease. The purpose of this study was to determine the effects of daily prune consumption on inflammatory...
Goodness-of-fit tests are important to assess how well a model fits a set of observations. Hosmer-Lemeshow (HL) test is a popular and commonly used method to assess the goodness-of-fit for logistic regression. However, there are two...
Characterization of the Subcellular Localization of ORF52/KicGAS and Functional Roles during the Life Cycles of Kaposi's Sarcoma-Associated Herpesvirus
Kaposi's sarcoma-associated herpesvirus (KSHV) is a gammaherpesvirus that causes Kaposi's sarcoma (KS) and two lymphoproliferative diseases. We previously reported KSHV ORF52/KicGAS (KSHV inhibitor of cGAS) to inhibit cGAS (cyclic GMP...
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
