Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.
As one of the leading causes of disease burden and disability in the world, Major Depressive Disorder (MDD) is a persistent and ever expanding financial and public health concern. MDD is quite prevalent in children and adolescents with...
Hepatitis C virus (HCV) infection leads to acute and chronic liver disease for thousands of people every year. With the absence of an effective treatment method, new classes of anti-HCV therapies are needed. Cyclosporine (CsA) and its...
The hexokinase family of enzymes catalyzes the ATP-dependent phosphorylation of glucose to generate glucose 6-phosphate and ADP. Consistent with highly evolved catalysts, hexokinases I-III possess high apparent substrate affinities (low...
Early life experiences play a major role in adult onset psychopathology. Childhood maltreatment, whether physical or emotional, is linked to mental illness and behavioral malfunctioning. Individuals who are emotionally, physically, or...
La related proteins (LARPs) form a superfamily of 7 distinct, homologous RNA regulatory protein which utilize a tandem La domain and ribonucleotide recognition motif (RRM), termed the La module, to recognize their individual RNA targets....
Some of the material in is restricted to members of the community. By logging in, you may be able to gain additional access to certain collections or items. If you have questions about access or logging in, please use the form on the Contact Page.