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Genome-wide association study identifies 74 loci associated with educational attainment.

Full Title:

Genome-wide association study identifies 74 loci associated with educational attainment.

Creator:

Okbay, Aysu, Beauchamp, Jonathan P, Fontana, Mark Alan, Lee, James J, Pers, Tune H, Rietveld, Cornelius A, Turley, Patrick, Chen, Guo-Bo, Emilsson, Valur, Meddens, S Fleur W, Oskarsson, Sven, Pickrell, Joseph K, Thom, Kevin, Timshel, Pascal, de Vlaming, Ronald, Abdellaoui, Abdel, Ahluwalia, Tarunveer S, Bacelis, Jonas, Baumbach, Clemens, Bjornsdottir, Gyda, Brandsma, Johannes H, Pina Concas, Maria, Derringer, Jaime, Furlotte, Nicholas A, Galesloot, Tessel E, Girotto, Giorgia, Gupta, Richa, Hall, Leanne M, Harris, Sarah E, Hofer, Edith, Horikoshi, Momoko, Huffman, Jennifer E, Kaasik, Kadri, Kalafati, Ioanna P, Karlsson, Robert, Kong, Augustine, Lahti, Jari, van der Lee, Sven J, deLeeuw, Christiaan, Lind, Penelope A, Lindgren, Karl-Oskar, Liu, Tian, Mangino, Massimo, Marten, Jonathan, Mihailov, Evelin, Miller, Michael B, van der Most, Peter J, Oldmeadow, Christopher, Payton, Antony, Pervjakova, Natalia, Peyrot, Wouter J, Qian, Yong, Raitakari, Olli, Rueedi, Rico, Salvi, Erika, Schmidt, Börge, Schraut, Katharina E, Shi, Jianxin, Smith, Albert V, Poot, Raymond A, St Pourcain, Beate, Teumer, Alexander, Thorleifsson, Gudmar, Verweij, Niek, Vuckovic, Dragana, Wellmann, Juergen, Westra, Harm-Jan, Yang, Jingyun, Zhao, Wei, Zhu, Zhihong, Alizadeh, Behrooz Z, Amin, Najaf, Bakshi, Andrew, Baumeister, Sebastian E, Biino, Ginevra, Bønnelykke, Klaus, Boyle, Patricia A, Campbell, Harry, Cappuccio, Francesco P, Davies, Gail, De Neve, Jan-Emmanuel, Deloukas, Panos, Demuth, Ilja, Ding, Jun, Eibich, Peter, Eisele, Lewin, Eklund, Niina, Evans, David M, Faul, Jessica D, Feitosa, Mary F, Forstner, Andreas J, Gandin, Ilaria, Gunnarsson, Bjarni, Halldórsson, Bjarni V, Harris, Tamara B, Heath, Andrew C, Hocking, Lynne J, Holliday, Elizabeth G, Homuth, Georg, Horan, Michael A, Hottenga, Jouke-Jan, de Jager, Philip L, Joshi, Peter K, Jugessur, Astanand, Kaakinen, Marika A, Kähönen, Mika, Kanoni, Stavroula, Keltigangas-Järvinen, Liisa, Kiemeney, Lambertus A L M, Kolcic, Ivana, Koskinen, Seppo, Kraja, Aldi T, Kroh, Martin, Kutalik, Zoltan, Latvala, Antti, Launer, Lenore J, Lebreton, Maël P, Levinson, Douglas F, Lichtenstein, Paul, Lichtner, Liewald, David C M, Loukola, Anu, Madden, Pamela A, Mägi, Reedik, Mäki-Opas, Tomi, Marioni, Riccardo E, Marques-Vidal, Pedro, Meddens, Gerardus A, McMahon, George, Meisinger, Christa, Meitinger, Thomas, Milaneschi, Yusplitri, Milani, Lili, Montgomery, Grant W, Myhre, Ronny, Nelson, Christopher P, Nyholt, Dale R, Ollier, William E R, Palotie, Aarno, Paternoster, Lavinia, Pedersen, Nancy L, Petrovic, Katja E, Porteous, David J, Räikkönen, Katri, Ring, Susan M, Robino, Antonietta, Rostapshova, Olga, Rudan, Igor, Rustichini, Aldo, Salomaa, Veikko, Sanders, Alan R, Sarin, Antti-Pekka, Schmidt, Helena, Scott, Rodney J, Smith, Blair H, Smith, Jennifer A, Staessen, Jan A, Steinhagen-Thiessen, Elisabeth, Strauch, Konstantin, Terracciano, Antonio, Tobin, Martin D, Ulivi, Sheila, Vaccargiu, Simona, Quaye, Lydia, van Rooij, Frank J A, Venturini, Cristina, Vinkhuyzen, Anna A E, Völker, Uwe, Völzke, Henry, Vonk, Judith M, Vozzi, Diego, Waage, Johannes, Ware, Erin B, Willemsen, Gonneke, Attia, John R, Bennett, David A, Berger, Bertram, Lars, Bisgaard, Hans, Boomsma, Dorret I, Borecki, Ingrid B, Bültmann, Ute, Chabris, Christopher F, Cucca, Francesco, Cusi, Daniele, Deary, Ian J, Dedoussis, George V, van Duijn, Cornelia M, Eriksson, Johan G, Franke, Barbara, Franke, Lude, Gasparini, Paolo, Gejman, Pablo V, Gieger, Christian, Grabe, Hans-Jörgen, Gratten, Jacob, Groenen, Patrick J F, Gudnason, Vilmundur, van der Harst, Pim, Hayward, Caroline, Hinds, Hoffmann, Wolfgang, Hyppönen, Elina, Iacono, William G, Jacobsson, Bo, Järvelin, Marjo-Riitta, Jöckel, Karl-Heinz, Kaprio, Jaakko, Kardia, Sharon L R, Lehtimäki, Terho, Lehrer, Steven F, Magnusson, Patrik K E, Martin, Nicholas G, McGue, Matt, Metspalu, Andres, Pendleton, Neil, Penninx, Brenda W J H, Perola, Markus, Pirastu, Nicola, Pirastu, Mario, Polasek, Ozren, Posthuma, Danielle, Power, Christine, Province, Samani, Nilesh J, Schlessinger, David, Schmidt, Reinhold, Sørensen, Thorkild I A, Spector, Tim D, Stefansson, Kari, Thorsteinsdottir, Unnur, Thurik, A Roy, Timpson, Nicholas J, Tiemeier, Henning, Tung, Joyce Y, Uitterlinden, André G, Vitart, Veronique, Vollenweider, Weir, David R, Wilson, James F, Wright, Alan F, Conley, Dalton C, Krueger, Robert F, Davey Smith, Hofman, Albert, Laibson, David I, Medland, Meyer, Michelle N, Yang, Jian, Johannesson, Magnus, Visscher, Peter M, Esko, Tõnu, Koellinger, Philipp D, Cesarini, Benjamin, Daniel J

Description:

Educational attainment is strongly influenced by social and other environmental factors, but genetic factors are estimated to account for at least 20% of the variation across individuals. Here we report the results of a genome-wide...

Date:

2016-05-26

Format:

journal article, text

Collection:

Department of Geriatrics

Identifiers:

FSU_pmch_27225129, 10.1038/nature17671, PMC4883595, 27225129, nature17671

URLs:

http://purl.flvc.org/fsu/fd/FSU_pmch_27225129

Repository ID:

fsu:623043

Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers

Full Title:

Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers

Creator:

Hartz, Sarah, Short, Susan, Saccone, Nancy, Culverhouse, Robert, Chen, LiShiun, Schwantes-An, Tae-Hwi, Coon, Hilary, Han, Younghun, Stephens, Sun, Juzhong, Chen, Xiangning, Ducci, Francesca, Dueker, Nicole, Franceschini, Nora, Frank, Josef, Geller, Frank, Gubjartsson, Daniel, Hansel, Nadia, Jiang, Chenhui, Keskitalo-Vuokko, Kaisu, Liu, Zhen, Lyytikäinen, Leo-Pekka, Michel, Martha, Rawal, Rajesh, Rosenberger, Albert, Scheet, Paul A. (Paul Anthony), Shaffer, John, Teumer, Alexander, Thompson, Vink, Jacqueline, Vogelzangs, Wenzlaff, Angela, Wheeler, William, Xiao, Xiangjun, Yang, Bao-Zhu, Aggen, Steven, Balmforth, Anthony, Baumeister, Sebastian, Beaty, Terri H., Bennett, Siiri, Bergen, Andrew, Boyd, Heather, Broms, Ulla, Campbell, Harry, Chatterjee, Nilanjan, Chen, Jingchun, Cheng, Yu-Ching, Cichon, Sven, Couper, David, Cucca, Francesco, Dick, Danielle M. (Danielle Marie), Foroud, Tatiana, Furberg, Helena, Giegling, Ina, Gu, Fangyi, Hall, A. S. (Alistair Scott), Hällfors, Jenni, Han, Shizhong, Hartmann, Annette, Hayward, Caroline, Heikkilä, Kauko, Hewitt, John K., Hottenga, Jouke-Jan, Jensen, Majken, Jousilahti, Pekka, 1955-, Kaakinen, Marika, Kittner, Konte, Bettina, Korhonen, Tellervo, Landi, Maria-Teresa, Laatikainen, Tiina, Leppert, Mark, Levy, Mathias, Rasika, McNeil, Medland, Montgomery, Grant, Muley, Thomas, Murray, Tanda, Nauck, Matthias, North, Kari, Pergadia, Michele, Polasek, Ozren, Ramos, Erin Michele, Ripatti, Samuli, Risch, Ruczinski, Ingo, Rudan, Igor, Salomaa, Veikko, Schlessinger, Styrkársdóttir, Unnur, Terracciano, Antonio, Uda, Manuela, Willemsen, Gonneke, Wu, Xifeng, Abecasis, Gonçalo, Barnes, Kathleen, Bickeböller, Heike, Boerwinkle, Eric, Boomsma, Dorret, Caporaso, Neil, Duan, Jubao, Edenberg, Howard, Francks, Clyde, Gejman, Pablo, Gelernter, Joel, Grabe, Hans, Hops, Hyman, Jarvelin, Marjo-Riitta, Viikari, Jorma, Kähönen, Mika, Kendler, Kenneth S., 1950-, Lehtimäki, Terho, Levinson, Douglas, Marazita, Mary, Marchini, Jonathan, Melbye, Mads, Mitchell, Braxton, Murray, Jeffrey, Nöthen, Markus, Penninx, Brenda, Raitakari, Olli, Rietschel, Marcella, Rujescu, Dan, Samani, Nilesh J., Sanders, Alan, Schwartz, Ann, Shete, Sanjay, Shi, Jianxin, Spitz, Margaret R., Stefansson, Swan, Gary, Thorgeirsson, Thorgeir, Völzke, Henry, Wei, Qingyi, Wichmann, H.-Erich (Heinz-Erich), 1946-, Amos, Christopher I., Breslau, Naomi, Cannon, Dale S., Ehringer, Marissa, Grucza, Richard, Hatsukami, Dorothy, Heath, Johnson, Kaprio, Jaakko, 1951-, Madden, Pamela, Martin, Nicholas G., Stevens, Victoria, Stitzel, Jerry, Weiss, Kraft, Peter, Bierut, Laura

Description:

CONTEXT: Recent studies have shown an association between cigarettes per day (CPD) and a nonsynonymous single-nucleotide polymorphism in CHRNA5, rs16969968. OBJECTIVE: To determine whether the association between rs16969968 and smoking...

Date:

2012

Format:

text

Collection:

Department of Geriatrics

Identifiers:

FSU_migr_geriatrics_faculty_publications-0040, 10.1001/archgenpsychiatry.2012.124

URLs:

http://dx.doi.org/10.1001/archgenpsychiatry.2012.124, http://purl.flvc.org/fsu/fd/FSU_migr_geriatrics_faculty_publications-0040

Repository ID:

fsu:207715

Meta-analysis of Genome-Wide Association Studies for Extraversion

Full Title:

Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium.

Creator:

van den Berg, Stéphanie M, de Moor, Marleen H M, Verweij, Karin J H, Krueger, Robert F, Luciano, Michelle, Arias Vasquez, Alejandro, Matteson, Lindsay K, Derringer, Jaime, Esko, Tõnu, Amin, Najaf, Gordon, Scott D, Hansell, Narelle K, Hart, Amy B, Seppälä, Ilkka, Huffman, Jennifer E, Konte, Bettina, Lahti, Jari, Lee, Minyoung, Miller, Mike, Nutile, Teresa, Tanaka, Toshiko, Teumer, Alexander, Viktorin, Wedenoja, Juho, Abdellaoui, Abdel, Abecasis, Goncalo R, Adkins, Daniel E, Agrawal, Arpana, Allik, Jüri, Appel, Katja, Bigdeli, Timothy B, Busonero, Fabio, Campbell, Harry, Costa, Paul T, Smith, George Davey, Davies, Gail, de Wit, Harriet, Ding, Jun, Engelhardt, Barbara E, Eriksson, Johan G, Fedko, Iryna O, Ferrucci, Luigi, Franke, Barbara, Giegling, Ina, Grucza, Richard, Hartmann, Annette M, Heath, Andrew C, Heinonen, Kati, Henders, Anjali K, Homuth, Georg, Hottenga, Jouke-Jan, Iacono, William G, Janzing, Joost, Jokela, Markus, Karlsson, Robert, Kemp, John P, Kirkpatrick, Matthew G, Latvala, Antti, Lehtimäki, Terho, Liewald, David C, Madden, Pamela A F, Magri, Chiara, Magnusson, Patrik K E, Marten, Jonathan, Maschio, Andrea, Mbarek, Hamdi, Medland, Sarah E, Mihailov, Evelin, Milaneschi, Yuri, Montgomery, Grant W, Nauck, Matthias, Nivard, Michel G, Ouwens, Klaasjan G, Palotie, Aarno, Pettersson, Erik, Polasek, Ozren, Qian, Yong, Pulkki-Råback, Laura, Raitakari, Olli T, Realo, Anu, Rose, Richard J, Ruggiero, Daniela, Schmidt, Carsten O, Slutske, Wendy S, Sorice, Rossella, Starr, John M, St Pourcain, Beate, Sutin, Angelina R, Timpson, Nicholas J, Trochet, Holly, Vermeulen, Sita, Vuoksimaa, Eero, Widen, Elisabeth, Wouda, Jasper, Wright, Margaret J, Zgaga, Lina, Porteous, David, Minelli, Alessandra, Palmer, Abraham A, Rujescu, Dan, Ciullo, Marina, Hayward, Caroline, Rudan, Igor, Metspalu, Andres, Kaprio, Jaakko, Deary, Ian J, Räikkönen, Katri, Wilson, James F, Keltikangas-Järvinen, Liisa, Bierut, Laura J, Hettema, Grabe, Hans J, Penninx, Brenda W J H, van Duijn, Cornelia M, Evans, David M, Schlessinger, Pedersen, Nancy L, Terracciano, Antonio, McGue, Matt, Martin, Nicholas G, Boomsma, Dorret I

Description:

Extraversion is a relatively stable and heritable personality trait associated with numerous psychosocial, lifestyle and health outcomes. Despite its substantial heritability, no genetic variants have been detected in previous genome...

Date:

2016-03-01

Format:

journal article, text

Collection:

Department of Behavioral Sciences and Social Medicine

Identifiers:

FSU_pmch_26362575, 10.1007/s10519-015-9735-5, PMC4751159, 26362575

URLs:

http://purl.flvc.org/fsu/fd/FSU_pmch_26362575

Repository ID:

fsu:620366

Meta-Analysis and Imputation Refines the Association of 15q25 with Smoking Quantity

Full Title:

Meta-Analysis and Imputation Refines the Association of 15q25 with Smoking Quantity

Creator:

Liu, Jason, Tozzi, Federica, Waterworth, Dawn, Pillai, Sreekumar, Muglia, Pierandrea, Middleton, Lefkos, Berrettini, Wade, Knouff, Christopher, Yuan, Xin, Waeber, Gérard, Vollenweider, Peter, Preisig, Martin, Wareham, Nicholas, Zhao, Jing, Loos, Ruth, Barroso, Inês, Khaw, Kay-Tee, Grundy, Scott M., Barter, Philip, Mahley, Robert, Kesaniemi, Antero, McPherson, Vincent, John, Strauss, Kennedy, James, Farmer, Anne, McGuffin, Day, Richard, Matthews, Keith, Bakke, Per, Gulsvik, A. (Amund), Lucae, Susanne, Ising, Marcus, Brueckl, Tanja, Horstmann, Sonja, Wichmann, H.-Erich (Heinz-Erich), 1946-, Rawal, Rajesh, Dahmen, Norbert, Lamina, Claudia, Polasek, Ozren, Zgaga, Lina, Huffman, Jennifer, Campbell, Susan, Kooner, Jaspal, Chambers, Burnett, Mary, Devaney, Joseph, Pichard, Augusto, Kent, Kenneth, Satler, Lowell, Lindsay, Waksman, Ron, Epstein, Stephen, Wilson, James F. (James Flett), Wild, Sarah, Campbell, Harry, Vitart, Veronique, Reilly, Muredach, Li, Mingyao, Qu, Liming, Wilensky, Matthai, William, Hakonarson, Hakon, Rader, Daniel, Franke, Andre, Wittig, Michael, Schäfer, Arne, Uda, Manuela, Terracciano, Antonio, Xiao, Xiangjun, Busonero, Fabio, Scheet, Paul A. (Paul Anthony), Schlessinger, David, St Clair, Rujescu, Dan, Abecasis, Gonçalo, Grabe, Hans, Teumer, Alexander, Völzke, Henry, Petersmann, Astrid, John, Ulrich, Rudan, Igor, Hayward, Caroline, Wright, Alan, Kolcic, Ivana, Wright, Benjamin, Thompson, Balmforth, Anthony, Hall, A. S. (Alistair Scott), Samani, Nilesh J., Anderson, Carl, Ahmad, Tariq, Mathew, Parkes, Miles, Satsangi, Jack, Caulfield, Mark, Munroe, Patricia, Farrall, Dominiczak, A. F., Worthington, Jane, Thomson, Wendy, Eyre, Steve, Barton, Mooser, Vincent, Francks, Clyde, Marchini, Jonathan

Description:

Smoking is a leading global cause of disease and mortality. We established the Oxford-GlaxoSmithKline study (Ox-GSK) to perform a genome-wide meta-analysis of SNP association with smoking-related behavioral traits. Our final data set...

Date:

2010

Format:

text

Collection:

Department of Geriatrics

Identifiers:

FSU_migr_geriatrics_faculty_publications-0018, 10.1038/ng.572

URLs:

http://dx.doi.org/10.1038/ng.572, http://purl.flvc.org/fsu/fd/FSU_migr_geriatrics_faculty_publications-0018

Repository ID:

fsu:207693

GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment

Full Title:

GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment

Creator:

Rietveld, Cornelius, Medland, Sarah, Derringer, Jaime, Yang, Jian, Esko, Tönu, Martin, Nicolas, Westra, Harm-Jan, Shakhbazov, Konstantin, Abdellaoui, Abdel, Agrawal, Arpana, Albrecht, Eva, Alizadeh, Behrooz, Amin, Najaf, Barnard, John, Baumeister, Sebastian, Benke, Kelly, Bielak, Lawrence, Boatman, Jeffrey A., Boyle, Patricia, Davies, Gail, de Leeuw, Christiaan, Eklund, Niina, Evans, Daniel, Ferhmann, Rudolf, Fischer, Krista, Gieger, Christian, Gjessing, Håkon K, Hägg, Sara, Harris, Jennifer, Hayward, Caroline, Holzapfel, Christina, Ibrahim-Verbaas, Carla, Ingelsson, Erik, Jacobsson, Bo, Joshi, Peter, Jugessur, Astanand, Kaakinen, Marika, Kanoni, Stavroula, Karjalainen, Juha, Kolcic, Ivana, Kristiansson, Kati, Kutalik, Zoltán, Lahti, Jari, Lee, Sang, Lin, Peng, Lind, Penelope, Liu, Yongmei, Lohman, Kurt, Loitfelder, Marisa, McMahon, George, Vidal, Pedro, Meirelles, Osorio, Milani, Lili, Myhre, Ronny, Nuotio, Marja-Liisa, Oldmeadow, Christopher, Petrovic, Katja, Peyrot, Wouter, Polasek, Ozren, Quaye, Lydia, Reinmaa, Rice, Rizzi, Thais, Schmidt, Helena, Schmidt, Reinhold, 1958-, Smith, Albert, Smith, Tanaka, Toshiko, Terracciano, Antonio, van der Loos, Matthijs, Vitart, Veronique, Völzke, Henry, Wellmann, Jürgen, Yu, Lei, Zhao, Wei, Allik, Jüri, Attia, Bandinelli, Stefania, Bastardot, François, Beauchamp, Jonathan, Bennett, David, Berger, Klaus, Bierut, Laura, Boomsma, Dorret, Bültmann, Ute, Campbell, Harry, Chabris, Cherkas, Lynn, Chung, Mina, Cucca, Francesco, de Andrade, Mariza, De Jager, Philip, De Neve, Jan-Emmanuel, Deary, Ian J., Dedoussis, Deloukas, Panos, Dimitriou, Maria, Eiríksdóttir, Guðny, Elderson, Martin, Eriksson, Johan, Evans, Faul, Jessica, Ferrucci, Luigi, Garcia, Melissa, Grönberg, Henrik, Guðnason, Vilmundur, Hall, Per, Harris, Juliette, Harris, Tamara, Hastie, Nicholas, Heath, Andrew, Hernandez, Dena, Hoffmann, Wolfgang, Hofman, Adriaan, Holle, Rolf, Holliday, Elizabeth, Hottenga, Jouke-Jan, Iacono, William, Illig, Thomas, Järvelin, Marjo-Riitta, Kähönen, Mika, Kaprio, Jaakko, 1951-, Kirkpatrick, Robert, Kowgier, Matthew, Latvala, Antti, Launer, Lenore, Lawlor, Debbie, Lehtimäki, Terho, Li, Jingmei, Lichtenstein, Paul, Lichtner, Liewald, Madden, Pamela, Magnusson, Patrik, Mäkinen, Tomi, Masala, Marco, McGue, Metspalu, Andres, Mielck, Andreas, Miller, Michael, Montgomery, Grant, Mukherjee, Sutapa, Nyholt, Dale, Oostra, Ben A., 1946-, Palmer, Lyle, Palotie, Aarno, Penninx, Brenda, Perola, Markus, Peyser, Preisig, Räikkönen, Katri, Raitakari, Olli, Realo, Anu, Ring, Susan, Ripatti, Samuli, Rivadeneira, Fernando, Rudan, Igor, Rustichini, Aldo, Salomaa, Veikko, Sarin, Antti-Pekka, Schlessinger, Scott, Rodney, Snieder, Harold, St Pourcain, Beate, Starr, John M., Sul, Jae, Surakka, Ida, Svento, Rauli, Teumer, Alexander, Tiemeier, Henning, van Rooij, Frank, Van Wagoner, Vartiainen, Erkki, Viikari, Jorma, Vollenweider, Vonk, Judith, Waeber, Gérard, Weir, Wichmann, H.-Erich (Heinz-Erich), Widen, Elisabeth, Willemsen, Gonneke, Wilson, James F. (James Flett), Wright, Alan, Conley, Dalton, Smith, George Davey, Franke, Lude, Groenen, Patrick, Hofman, Johannesson, Magnus, Kardia, Sharon, Krueger, Robert F., Laibson, Martin, Nicholas G., Meyer, Michelle, Posthuma, Danielle, Thurik, A. R. (A. Roy), Timpson, Uitterlinden, André G., van Duijn, Cornelia, Visscher, Benjamin, Cesarini, Koellinger, Philipp

Description:

A genome-wide association study (GWAS) of educational attainment was conducted in a discovery sample of 101, 069 individuals and a replication sample of 25, 490. Three independent single-nucleotide polymorphisms (SNPs) are genome-wide...

Date:

2013

Format:

text

Collection:

Department of Geriatrics

Identifiers:

FSU_migr_geriatrics_faculty_publications-0007, 10.1126/science.1235488

URLs:

http://dx.doi.org/10.1126/science.1235488, http://purl.flvc.org/fsu/fd/FSU_migr_geriatrics_faculty_publications-0007

Repository ID:

fsu:207682

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